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Found 4 Enz. Inhib. hit(s) with Target = 'L-lactate dehydrogenase' and Ligand = 'BDBM23223'
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  2.03E+3nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  2.64E+3nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  3.97E+3nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase(Bos taurus (Bovine))
University of Mississippi

LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  6.90E+3nMAssay Description:Enzyme assay using recombinant pfLDH and mLDH (bovine heart).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed