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Found 2 Enz. Inhib. hit(s) with Target = 'L-lactate dehydrogenase A chain' and Ligand = 'BDBM537074'
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM537074(US11247971, Cmpd ID 397)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM537074(US11247971, Cmpd ID 397)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of LDHA in human MIA PaCa2 cells assessed as reduction in lactate production incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed