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Found 3 Enz. Inhib. hit(s) with Target = 'LIM domain kinase 1' and Ligand = 'BDBM50591084'
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591084(CHEMBL5186508)
Affinity DataIC50:  575nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591084(CHEMBL5186508)
Affinity DataIC50:  631nMAssay Description:Inhibition of PAK mediated recombinant LIMK1 phosphorylation (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591084(CHEMBL5186508)
Affinity DataKd:  386nMAssay Description:Binding affinity to recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells assessed as dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed