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Found 3 Enz. Inhib. hit(s) with Target = 'Lanosterol 14-alpha demethylase' and Ligand = 'BDBM628820'
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Kineta

US Patent
LigandPNGBDBM628820(US20230339890, Compound 90 | US20230339890, Compou...)
Affinity DataIC50: <100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Kineta

US Patent
LigandPNGBDBM628820(US20230339890, Compound 90 | US20230339890, Compou...)
Affinity DataIC50: <100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Kineta

US Patent
LigandPNGBDBM628820(US20230339890, Compound 90 | US20230339890, Compou...)
Affinity DataIC50: <100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent