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Found 4 Enz. Inhib. hit(s) with Target = 'Lanosterol synthase' and Ligand = 'BDBM50128054'
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128054(Allyl-{6-[1-(4-bromo-phenyl)-isoquinolin-6-yloxy]-...)
Affinity DataIC50:  3.47nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128054(Allyl-{6-[1-(4-bromo-phenyl)-isoquinolin-6-yloxy]-...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128054(Allyl-{6-[1-(4-bromo-phenyl)-isoquinolin-6-yloxy]-...)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128054(Allyl-{6-[1-(4-bromo-phenyl)-isoquinolin-6-yloxy]-...)
Affinity DataIC50:  3.5nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed