Found 4 Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM50436423' TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length wild-type LRRK2 (unknown origin) using biotinylated ezrin/radaxin/meosin peptide as substrate measured after 1 hrMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant wild type LRRK2 using biotin-LRRKtide as substrate preincubated for 15 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of LRRK2 (unknown origin)More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Inhibition of LRRK2 G2019S mutant-induced neuronal toxicity in human cortical neuronsMore data for this Ligand-Target Pair
