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Found 2 Enz. Inhib. hit(s) with Target = 'Lys-gingipain' and Ligand = 'BDBM453357'
TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM453357(BDBM553861 | US10730826, Compound 51a)
Affinity DataIC50:  0.400nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain (Kgp) were measured in a fluorogenic assay similar t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM453357(BDBM553861 | US10730826, Compound 51a)
Affinity DataIC50:  0.440nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain (Kgp) were measured in a fluorogenic assay similar t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent