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Found 2 Enz. Inhib. hit(s) with Target = 'Lysine--tRNA ligase' and Ligand = 'BDBM50457621'
TargetLysine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50457621(CHEMBL578530 | GNF-Pf-5378)
Affinity DataIC50:  7.25E+3nMAssay Description:Inhibition of Plasmodium falciparum KRS expressed in Escherichia coli BL21 using tRNA(Lys) as substrate after 45 mins in presence of L-lysine by AMP-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine--tRNA ligase(Homo sapiens (Human))
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50457621(CHEMBL578530 | GNF-Pf-5378)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human KRS expressed in Escherichia coli BL21 using tRNA(Lys) as substrate after 1 hr in presence of L-lysine by AMP-GLO assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed