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Found 2 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5A' and Ligand = 'BDBM281129'
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281129(US10022354, Example 69)
Affinity DataIC50:  0.110nMpH: 7.0 T: 2°CAssay Description:Full length KDM5A enzyme was expressed and purified inhouse. Biotin-H3K4me3 peptide was purchased from New England Biolabs. HTRF reagents (containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281129(US10022354, Example 69)
Affinity DataIC50:  105nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged KDM5A expressed in baculovirus infected Sf9 insect cells using H3K4me3 peptide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed