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Found 4 Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM338739'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM338739(3-(trans-2-(cyclobutyl- amino)cyclopropyl)-N- (5-m...)
Affinity DataIC50:  160nMAssay Description:A test compound dissolved in 2.5% DMSO was added by 4 μL to 3 μL reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM338739(3-(trans-2-(cyclobutyl- amino)cyclopropyl)-N- (5-m...)
Affinity DataIC50:  170nMAssay Description:A test compound dissolved in 2.5% DMSO was added by 4 μL to 3 μL reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM338739(3-(trans-2-(cyclobutyl- amino)cyclopropyl)-N- (5-m...)
Affinity DataIC50:  360nMAssay Description:A test compound dissolved in 2.5% DMSO was added by 4 μL to 3 μL reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM338739(3-(trans-2-(cyclobutyl- amino)cyclopropyl)-N- (5-m...)
Affinity DataIC50:  450nMAssay Description:A test compound dissolved in 2.5% DMSO was added by 4 μL to 3 μL reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing...More data for this Ligand-Target Pair
In DepthDetails US Patent