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Found 2 Enz. Inhib. hit(s) with Target = 'Lysophosphatidic acid receptor 1' and Ligand = 'BDBM50398091'
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50398091(CHEMBL2182049 | US9321738, 12)
Affinity DataIC50:  18.8nMT: 2°CAssay Description:Test compounds were prepared by adding 90 μL of HBSS/20 mM HEPES/0.1% BSA buffer to 2 μL of serially diluted compounds. To prepare serial dilut...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50398091(CHEMBL2182049 | US9321738, 12)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human recombinant LPA1 expressed in chem-1 cells assessed as inhibition of LPA-induced intracellular calcium mobilization incu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed