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Found 2 Enz. Inhib. hit(s) with Target = 'Lysosomal acid glucosylceramidase' and Ligand = 'BDBM108417'
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108417(US8604206, 6)
Affinity DataKi:  3.06nM IC50:  5.80nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108417(US8604206, 6)
Affinity DataKi:  13.6nM IC50:  25.9nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent