Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Lysosomal acid glucosylceramidase' and Ligand = 'BDBM50196515'
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50196515(CHEMBL3913022 | US10167270, Compound 8f)
Affinity DataIC50:  1.12E+3nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50196515(CHEMBL3913022 | US10167270, Compound 8f)
Affinity DataIC50:  1.40E+3nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50196515(CHEMBL3913022 | US10167270, Compound 8f)
Affinity DataIC50:  1.40E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed