Found 4 Enz. Inhib. hit(s) with Target = 'Lysosomal acid glucosylceramidase' and Ligand = 'BDBM50196626' TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Northwestern University Feinberg School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
