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Found 3 Enz. Inhib. hit(s) with Target = 'Lysosomal alpha-glucosidase' and Ligand = 'BDBM50583383'
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50583383(CHEMBL5028005 | US20230339856, Compound (IIb3))
Affinity DataKi:  4.70nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50583383(CHEMBL5028005 | US20230339856, Compound (IIb3))
Affinity DataKi:  1.08E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50583383(CHEMBL5028005 | US20230339856, Compound (IIb3))
Affinity DataIC50:  2.96E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
In DepthDetails US Patent