Found 9 Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM50130693' TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Inhibition of human Mnk2a using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measured after 90 mins by ...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of MNK2 (unknown origin) using S3 as substrate measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MNK2 (unknown origin)More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human Mnk2a using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measured after 45 mins by ...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MNK2 (unknown origin) expressed in HEK293 cells assessed as decrease in eIF4E phosphorylation at Ser209 residues by Western blot analys...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MKN2 (unknown origin) in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human His6-tagged Mnk2 expressed in Escherichia coli assessed as phosphorylation of eukaryotic translation initiation factor 4EMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MNK2 (unknown origin) using eIF4E as a substrate in presence of ATPMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataIC50: 6.27E+3nMAssay Description:Inhibition of human recombinant full length GST-tagged MNK2 expressed in insect cells using S6 peptide as substrate in presence of [gamma-33P]-ATP in...More data for this Ligand-Target Pair
