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Found 3 Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM119043'
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119043(CHEMBL3085978 | US8674100, 60 | US9221797, 60)
Affinity DataIC50:  0.800nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM119043(CHEMBL3085978 | US8674100, 60 | US9221797, 60)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119043(CHEMBL3085978 | US8674100, 60 | US9221797, 60)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of FMS in mouse BMDM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed