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Found 5 Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50443123'
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443123(CHEMBL3086179 | US8674100, 26)
Affinity DataIC50:  3.20nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50443123(CHEMBL3086179 | US8674100, 26)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443123(CHEMBL3086179 | US8674100, 26)
Affinity DataIC50:  3.60nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443123(CHEMBL3086179 | US8674100, 26)
Affinity DataIC50:  3.70nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443123(CHEMBL3086179 | US8674100, 26)
Affinity DataIC50:  13nMAssay Description:Inhibition of FMS in mouse BMDM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed