Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Macrophage metalloelastase' and Ligand = 'BDBM194645'
TargetMacrophage metalloelastase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM194645(US9206139, 4)
Affinity DataIC50:  3.37E+3nMpH: 7.5Assay Description:A continuous assay is used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin, Mca), which is quenched b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM194645(US9206139, 4)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human MMP12 using Mca-PQGL-(3-[2, 4-dinitrophenyl]-L-2, 3-diaminopropionyl)-AR-OH as substrate after 2 to 4 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed