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Found 7 Enz. Inhib. hit(s) with Target = 'Macrophage migration inhibitory factor' and Ligand = 'BDBM92515'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataKi:  52nMAssay Description:Covalent inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli using 4-hydroxyphenyl pyruvic acid as substrate asses...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataKi:  570nM IC50:  2.40E+3nMpH: 6.5Assay Description:The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataKi:  570nMAssay Description:Inhibition of recombinant human MIF tautomerization expressed in Escherichia coli BL21/DE3 using HPP as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataIC50:  360nMAssay Description:Covalent inhibition of MIF (unknown origin) tautomerase activity using 4-hydroxyphenyl pyruvic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataIC50:  570nMAssay Description:Covalent inhibition of human MIF tautomerase activity expressed in Escherichia coli BL21 (DE3) using 4-hydroxyphenyl pyruvic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human MIF tautomerization expressed in Escherichia coli BL21/DE3 using dopa as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataIC50:  6.12E+3nMAssay Description:Inhibition of recombinant human full length MIF expressed in Escherichia coli BL21(DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed