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Found 6 Enz. Inhib. hit(s) with Target = 'Macrophage-stimulating protein receptor' and Ligand = 'BDBM50317323'
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  12nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  30nMAssay Description:Inhibition of RON phosphorylation in human HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  30nMAssay Description:Inhibition of RON phosphorylation in human PC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  50nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed