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Found 4 Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM50177716'
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  6.90nMAssay Description:The activity of unphosphorylated c-KIT kinase (c-KIT, SEQ ID NO: 2) was determined spectroscopically using a coupled pyruvate kinase/lactate dehydrog...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  27nMAssay Description:Inhibition of KIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  27nMAssay Description:Inhibition of wild type KIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant c-kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed