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Found 2 Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit [D816V]' and Ligand = 'BDBM469288'
TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM469288(US10807985, Compound 63 | US10829493, Example 63 o...)
Affinity DataIC50: <0.300nMAssay Description:PDGFRα (D842V):PDGFRα D842V assay at the apparent Michaelis-Menten constant(APPKM) for ATP: In each well of a 384-well assay plate, 7 nM of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM469288(US10807985, Compound 63 | US10829493, Example 63 o...)
Affinity DataIC50: <1nMAssay Description:In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V KIT (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of buffer (100 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent