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Found 3 Enz. Inhib. hit(s) with Target = 'Maternal embryonic leucine zipper kinase' and Ligand = 'BDBM50248925'
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50248925(CHEMBL4061117 | US10981896, Compound 22)
Affinity DataKi:  358nMAssay Description:Inhibition of His6-tagged MELK catalytic domain (1 to 340 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using Bcl-GL as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50248925(CHEMBL4061117 | US10981896, Compound 22)
Affinity DataIC50:  2.70E+3nMAssay Description:The top 10 hits from the 1 μM screening and derivatives of MELK-In-1 were subjected to the same assay conditions with varied inhibitor concentra...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50248925(CHEMBL4061117 | US10981896, Compound 22)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of His6-tagged MELK catalytic domain (1 to 340 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using Bcl-GL as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed