Found 4 Enz. Inhib. hit(s) with Target = 'Maternal embryonic leucine zipper kinase' and Ligand = 'BDBM50248946' TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
The University of Texas At Austin
Curated by ChEMBL
The University of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Inhibition of His6-tagged MELK catalytic domain (1 to 340 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using Bcl-GL as s...More data for this Ligand-Target Pair
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
The University of Texas At Austin
Curated by ChEMBL
The University of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:MELK and its substrate, Bcl-G were both recombinantly expressed and purified for use in screening assays (See Methods). 752 compounds from an in-hous...More data for this Ligand-Target Pair
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
The University of Texas At Austin
Curated by ChEMBL
The University of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:The top 10 hits from the 1 μM screening and derivatives of MELK-In-1 were subjected to the same assay conditions with varied inhibitor concentra...More data for this Ligand-Target Pair
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
The University of Texas At Austin
Curated by ChEMBL
The University of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of His6-tagged MELK catalytic domain (1 to 340 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using Bcl-GL as s...More data for this Ligand-Target Pair
