Affinity DataKi: 0.5nMAssay Description:Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity to mouse MC4RMore data for this Ligand-Target Pair
Affinity DataKi: 540nMAssay Description:Binding affinity to MC5RMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Antagonist activity at MC4R assessed as inhibition of alphaMSH-stimulated cAMP releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 170nMAssay Description:Agonist activity at MC4R assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair