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Found 3 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50263839'
TargetMelanocortin receptor 4(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50263839(CHEMBL4102353)
Affinity DataKi: <1.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R LBD expressed in HEK293 cell membranes incubated for 16 to 23 hrs in dark by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50263839(CHEMBL4102353)
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human MC4R expressed in low doxycyclin-treated HEK293 cell membranes assessed as increase in cAMP production after 45 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50263839(CHEMBL4102353)
Affinity DataEC50:  479nMAssay Description:Agonist activity at human MC4R expressed in high doxycyclin-treated HEK293 cell membranes assessed as increase in cAMP production after 15 mins by HT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed