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Found 4 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50500592'
TargetMelanocortin receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50500592(CHEMBL3752534)
Affinity DataIC50:  190nMAssay Description:Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 4 receptor expressed in HEK293 cells incubated for 40 mins by gamma count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50500592(CHEMBL3752534)
Affinity DataIC50:  1.10E+3nMAssay Description:Antagonist activity at human MC4R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50500592(CHEMBL3752534)
Affinity DataIC50:  1.10E+3nMAssay Description:Antagonist activity at human MC4R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50500592(CHEMBL3752534)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human melanocortin 4 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed