Found 17 Enz. Inhib. hit(s) with Target = 'Melanocyte-stimulating hormone receptor' and Ligand = 'BDBM50034922' TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Displacement of [125I]-[Nle4,d-Phe7]-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 388nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC1R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 615nMAssay Description:Displacement of [125I]NDP-MSH from Melanocortin 1 receptor at 10 uMMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonistic activity evaluated at melanocortin 1 receptor (MC1R) of mouse HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 25.6nMAssay Description:Functional activity at the mouse melanocortin 1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 20.1nMAssay Description:In vitro activaction of mouse recombinant Melanocortin-1 receptor.More data for this Ligand-Target Pair
Affinity DataEC50: 20.1nMAssay Description:Agonist activity to the mouse Melanocortin-1 receptor (mMC1R)More data for this Ligand-Target Pair
Affinity DataEC50: 52nMAssay Description:In vitro agonist potency for Mouse Melanocortin 1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 112nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells by CRE/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assayMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataEC50: 4.30nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells after 3 mins by cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at mouse melanocortin receptor 1 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 71nMAssay Description:Agonist activity at mouse melanocortin-1 receptor transfected in HEK293 cells after 6 hrs by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at mouse melanocortin receptor 1 expressed in HEK293 cells assessed as stimulation of intracellular cAMP accumulation incubated for ...More data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataEC50: 228nMAssay Description:effective concentration of peptide at 50% maximal cAMP accumulation on Melanocortin 1 receptorMore data for this Ligand-Target Pair
