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Found 4 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50143059'
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50143059(CHEMBL3758746)
Affinity DataEC50:  11nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50143059(CHEMBL3758746)
Affinity DataEC50:  22nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50143059(CHEMBL3758746)
Affinity DataEC50:  26nMAssay Description:Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50143059(CHEMBL3758746)
Affinity DataEC50:  11.5nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed