Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Ligand = 'BDBM186216'
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM186216(US9163015, 2)
Affinity DataEC50:  33nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM186216(US9163015, 2)
Affinity DataEC50:  68nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM186216(US9163015, 2)
Affinity DataEC50:  68nMAssay Description:Agonist activity at human mGlu4 receptor assessed as increase in calcium fluxMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM186216(US9163015, 2)
Affinity DataEC50:  68nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium flux prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM186216(US9163015, 2)
Affinity DataEC50:  67nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed