Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50071373'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataKi: 1.44E+3nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 872nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair