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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50154994'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50154994(2-[2-(5-Fluoro-3''-methyl-biphenyl-3-yl)-2H-tetraz...)
Affinity DataIC50:  1.47E+3nMAssay Description:Antagonistic activity of the compound against Metabotropic glutamate receptor 5 in [Ca2+] flux assay using glutamate (10 uM) as agonistMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50154994(2-[2-(5-Fluoro-3''-methyl-biphenyl-3-yl)-2H-tetraz...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro antagonistic activity against Metabotropic glutamate receptor 5 in [Ca2+] flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed