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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50207079'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50207079(4-(3-cyanophenyl)-N-(6-methylpyridin-2-yl)picolina...)
Affinity DataKi:  320nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50207079(4-(3-cyanophenyl)-N-(6-methylpyridin-2-yl)picolina...)
Affinity DataIC50:  7.30E+3nMAssay Description:Antagonist activity at mGluR5 expressed in CHO cells assessed as phosphoinositide hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed