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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50207080'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50207080(CHEMBL248141 | N-(6-methylpyridin-2-yl)-5-(pyridin...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50207080(CHEMBL248141 | N-(6-methylpyridin-2-yl)-5-(pyridin...)
Affinity DataIC50:  1.24E+4nMAssay Description:Antagonist activity at mGluR5 expressed in CHO cells assessed as phosphoinositide hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed