Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50207080'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.24E+4nMAssay Description:Antagonist activity at mGluR5 expressed in CHO cells assessed as phosphoinositide hydrolysisMore data for this Ligand-Target Pair