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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50337494'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337494(5-(phenylethynyl)isoindoline-1,3-dione | CHEMBL168...)
Affinity DataEC50:  5.90nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337494(5-(phenylethynyl)isoindoline-1,3-dione | CHEMBL168...)
Affinity DataEC50:  11nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed