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Found 2 Enz. Inhib. hit(s) with Target = 'Microtubule-associated protein tau' and Ligand = 'BDBM15236'
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant brain tau protein (412 amino acid residues) filament assembly expressed in Escherichia coli BL21(DE3) by electron mic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50: <3.00E+3nMAssay Description:Inhibition of His-tagged human brain tau 3R MBD aggregation after 16 hrs by thioflavin T fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed