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Found 1 Enz. Inhib. hit(s) with Target = 'Microtubule-associated protein tau' and Ligand = 'BDBM281567'
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281567(US10022461, Compound 18)
Affinity DataKi:  0.430nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails US Patent