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Found 4 Enz. Inhib. hit(s) with Target = 'Mineralocorticoid receptor' and Ligand = 'BDBM50443329'
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50443329(CHEMBL3086027)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]aldosterone from GST-tagged human mineralocorticoid receptor ligand binding domain after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50443329(CHEMBL3086027)
Affinity DataIC50:  191nMAssay Description:Displacement of [3H]aldosterone from GST-tagged human mineralocorticoid receptor ligand binding domain after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50443329(CHEMBL3086027)
Affinity DataIC50:  556nMAssay Description:Antagonist activity at human mineralocorticoid receptor ligand binding domain expressed in human Huh7 cells after 16 hrs by luciferase reporter gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50443329(CHEMBL3086027)
Affinity DataIC50:  1.31E+3nMAssay Description:Antagonist activity at human mineralocorticoid receptor ligand binding domain expressed in human Huh7 cells after 16 hrs by luciferase reporter gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed