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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 11/12/13/14' and Ligand = 'BDBM50122914'
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122914(6-(2-(2,4-difluorophenyl)imidazo[1,2-a]pyridin-3-y...)
Affinity DataIC50:  14nMAssay Description:Inhibition of Tumor necrosis factor alpha release from LPS-induced THP-1 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122914(6-(2-(2,4-difluorophenyl)imidazo[1,2-a]pyridin-3-y...)
Affinity DataIC50:  440nMAssay Description:Inhibition of LPS-induced p38-related Tumor necrosis factor alpha release in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed