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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 11/12/13/14' and Ligand = 'BDBM50222107'
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222107(CHEMBL93650)
Affinity DataIC50:  1.60nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222107(CHEMBL93650)
Affinity DataIC50:  65nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed