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Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 13' and Ligand = 'BDBM13533'
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  300nMAssay Description:Inhibition of P38deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  500nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  1.97E+3nMT: 2°CAssay Description:The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataKd:  78nMAssay Description:Binding constant for p38-delta kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed