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Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50352582'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352582(CHEMBL1825162 | US8772288, 52)
Affinity DataIC50:  72nMpH: 7.5 T: 2°CAssay Description:Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352582(CHEMBL1825162 | US8772288, 52)
Affinity DataIC50:  72nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352582(CHEMBL1825162 | US8772288, 52)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed