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Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM102563'
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM102563(US8536172, I-12)
Affinity DataIC50:  3nMAssay Description:Inhibition of human JNK1alpha1 using GST-tagged ATF2 as substrate preincubated for 10 mins prior to substrate addition measured after 30 mins by micr...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM102563(US8536172, I-12)
Affinity DataIC50:  3.10nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM102563(US8536172, I-12)
Affinity DataIC50:  17.9nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM102563(US8536172, I-12)
Affinity DataKd:  0.140nMAssay Description:Binding affinity to JNK1 (unknown origin)More data for this Ligand-Target Pair