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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM29315'
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM29315(2-amino-1,3,4-thiadiazole, 9)
Affinity DataIC50:  239nMAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM29315(2-amino-1,3,4-thiadiazole, 9)
Affinity DataIC50:  700nMAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed