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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM50379277'
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50379277(CHEMBL90825)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of C-terminal His6-tagged human JNK1alpha1 (1 to 364 residues) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in MKK7...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50379277(CHEMBL90825)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to JNK1 allosteric site by AS-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB