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Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM50392982'
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392982(CHEMBL2152382)
Affinity DataIC50:  44nMAssay Description:Inhibition of JNK1 after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392982(CHEMBL2152382)
Affinity DataIC50:  62nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392982(CHEMBL2152382)
Affinity DataKd:  62nMAssay Description:Binding affinity to T7-phage-tagged JNK1 by PCR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392982(CHEMBL2152382)
Affinity DataEC50:  1.01E+4nMAssay Description:Inhibition of JNK1-mediated c-jun phosphorylation in TNF-alpha stimulated human HK-2 cells after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed