Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM50505945'
Affinity DataIC50: 14nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Affinity DataIC50: 232nMAssay Description:Inhibition of V5 tagged human ASK1 expressed in HEK-293T cells assessed as reduction in T838 autophosphorylation incubated for 1 hrMore data for this Ligand-Target Pair