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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM524898'
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM524898((R)-10-Methyl-55-(4-methyl-1H-imidazol-1-yl)-14H-6...)
Affinity DataIC50: <100nMAssay Description:Table 2: Alternatively, the protein kinase activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Cor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM524898((R)-10-Methyl-55-(4-methyl-1H-imidazol-1-yl)-14H-6...)
Affinity DataIC50: <100nMAssay Description:Table 1: Briefly, 20 μL aliquots of a 1.5× stock of ASK1, STK Substrate 3 and Assay Buffer were distributed in the wells of a white 384 well Opt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent