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Found 2 Enz. Inhib. hit(s) with Target = 'Monocarboxylate transporter 1' and Ligand = 'BDBM214698'
TargetMonocarboxylate transporter 1(Homo sapiens (Human))TBA
LigandPNGBDBM214698(US9296728, 21)
Affinity DataIC50:  48nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents of The University of Minnesota

US Patent
LigandPNGBDBM214698(US9296728, 21)
Affinity DataIC50:  59nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent